TRPV4

TRPV4

Transient receptor potential cation channel, subfamily V, member 4 (Receptor de potencial transiente, subfamilia V, miembro 4, también conocido como TRPV4, es un gen humano.[1] [2]

Este gen codifica para TRPV4, un miembro de la familia tipo-OSM9 transient receptor potential channel (OTRPC) de la subfamilia transient receptor potential (TRP) perteneciente a la superfamilia de canales iónicos.[3] [4] [5] La proteína codificada es un [[[canal catiónico]]] no selectivo permeable a Ca2+ que se cree está involucrado en la regulación de la Presión osmótica sistémica.[6] Dos variantes transcripcionales han sido encontradas para este gen.[7]

Mirar También

  • TRPV

Referencias

  1. ↑ Strotmann R, Harteneck C, Nunnenmacher K, Schultz G, Plant TD (October 2000). «OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity». Nat. Cell Biol. 2 (10):  pp. 695–702. doi:10.1038/35036318. PMID 11025659. 
  2. ↑ Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S (October 2000). «Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor». Cell 103 (3):  pp. 525–35. doi:10.1016/S0092-8674(00)00143-4. PMID 11081638. 
  3. ↑ Harteneck C, Plant TD, Schultz G (April 2000). «From worm to man: three subfamilies of TRP channels». Trends Neurosci. 23 (4):  pp. 159–66. doi:10.1016/S0166-2236(99)01532-5. PMID 10717675. 
  4. ↑ Clapham DE, Julius D, Montell C, Schultz G (December 2005). «International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels». Pharmacol. Rev. 57 (4):  pp. 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. 
  5. ↑ Plant TD, Strotmann R (2007). «TRPV4». Handb Exp Pharmacol (179):  pp. 189–205. doi:10.1007/978-3-540-34891-7_11. PMID 17217058. 
  6. ↑ Harteneck C, Reiter B (February 2007). «TRP channels activated by extracellular hypo-osmoticity in epithelia». Biochem. Soc. Trans. 35 (Pt 1):  pp. 91–5. doi:10.1042/BST0350091. PMID 17233610. 
  7. ↑ «Entrez Gene: TRPV4 transient receptor potential cation channel, subfamily V, member 4».

Enlaces externos


Wikimedia foundation. 2010.

Игры ⚽ Нужна курсовая?

Mira otros diccionarios:

  • TRPV4 — Transient receptor potential cation channel, subfamily V, member 4, also known as TRPV4, is a human gene.cite journal | author = Strotmann R, Harteneck C, Nunnenmacher K, Schultz G, Plant TD | title = OTRPC4, a nonselective cation channel that… …   Wikipedia

  • TRPV — is a family of transient receptor potential ion channels.TRPV subunits contain three to five N terminal ankyrin repeats and can be activated through a variety of mechanisms. TRPV1 to TRPV4 can act as thermometers on a molecular level. TRPV1,… …   Wikipedia

  • PACSIN1 — Protein kinase C and casein kinase substrate in neurons 1 Rendering based on PDB 3ABH …   Wikipedia

  • PACSIN2 — Protein kinase C and casein kinase substrate in neurons 2 Rendering based on PDB 3ABH …   Wikipedia

  • PACSIN3 — Protein kinase C and casein kinase substrate in neurons 3 Identifiers Symbols PACSIN3; FLJ17861; SDPIII External IDs …   Wikipedia

  • TRP-Kanäle — Bezeichner Gen Name(n) TRPC, TRPV, TRPM, TRPN, TRPA, TRPP …   Deutsch Wikipedia

  • Calciumstoffwechsel — Übergeordnet Ionen Homöostase Gene Ontology …   Deutsch Wikipedia

  • Ion channel family — Pfam box Symbol = Ion trans Name = Ion channel (eukariotic) width =250 caption =Potassium channel KvAP, structure in a membrane like environment. Calculated hydrocarbon boundaries of the lipid bilayer are indicated by red and blue dots. Pfam=… …   Wikipedia

  • WNK4 — WNK lysine deficient protein kinase 4, also known as WNK4, is a human gene.cite web | title = Entrez Gene: WNK4 WNK lysine deficient protein kinase 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=65266|… …   Wikipedia

  • MAP7 — Microtubule associated protein 7, also known as MAP7, is a human gene.cite web | title = Entrez Gene: MAP7 microtubule associated protein 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=9053| accessdate …   Wikipedia

Compartir el artículo y extractos

Link directo
… Do a right-click on the link above
and select “Copy Link”