NSP6 (rotavirus)

NSP6 (rotavirus)

El Gen 11 del rotavirus codifica una proteína estructural, NSP5 y también codifica NSP6, de un cabo de la fase de lectura abierta.[1] En contraste con los otros rotavirus con proteínas no estructurales, NSP6 se encontró que tenía un alto índice de rotación, que se degrada completamente dentro de 2 horas de la síntesis. NSP6 resultó ser una secuencia de ácido nucleico independiente de la proteína de unión, con afinidades similares para ssRNA y dsRNA.[2]

Referencias

  1. Mohan KV, Atreya CD (December 2001). «Nucleotide sequence analysis of rotavirus gene 11 from two tissue culture-adapted ATCC strains, RRV and Wa». Virus Genes 23 (3):  pp. 321–9. doi:10.1023/A:1012577407824. PMID 11778700. 
  2. Rainsford EW, McCrae MA (December 2007). «Characterization of the NSP6 protein product of rotavirus gene 11». Virus Research 130 (1–2):  pp. 193–201. doi:10.1016/j.virusres.2007.06.011. PMID 17658646. 




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