- GTF2A1
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Subunidad 1 del factor iniciador de la transcripción IIA 
Estructura tridimensional de la proteína GTF2A1.HUGO 4646 Símbolo GTF2A1 Símbolos alt. MGC129969, MGC129970, TF2A1, TFIIA Datos genéticos Locus Cr. 14 q31.1 Bases de datos Entrez 2957 OMIM 600520 PDB 1nvp RefSeq NP_056943 UniProt P52655 La subunidad 1 del factor iniciador de la transcripción IIA (GTF2A1) es una proteína codificada en humanos por el gen gtf2A1.[1] [2]
Contenido
Interacciones
La proteína GTF2A1 ha demostrado ser capaz de interaccionar con:
Véase también
- Factor de transcripción II A
Referencias
- ↑ DeJong J, Roeder RG (Dec 1993). «A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA». Genes Dev 7 (11): pp. 2220–34. PMID 8224848.
- ↑ «Entrez Gene: GTF2A1 general transcription factor IIA, 1, 19/37kDa».
- ↑ DeJong, J; Bernstein R, Roeder R G (Apr. 1995). «Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 92 (8): pp. 3313–7. ISSN 0027-8424. PMID 7724559.
- ↑ Langelier, M F; Forget D, Rojas A, Porlier Y, Burton Z F, Coulombe B (Oct. 2001). «Structural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II». J. Biol. Chem. (United States) 276 (42): pp. 38652–7. doi:. ISSN 0021-9258. PMID 11509574.
- ↑ Ozer, J; Mitsouras K, Zerby D, Carey M, Lieberman P M (Jun. 1998). «Transcription factor IIA derepresses TATA-binding protein (TBP)-associated factor inhibition of TBP-DNA binding». J. Biol. Chem. (UNITED STATES) 273 (23): pp. 14293–300. ISSN 0021-9258. PMID 9603936.
- ↑ Solow, S; Salunek M, Ryan R, Lieberman P M (May. 2001). «Taf(II) 250 phosphorylates human transcription factor IIA on serine residues important for TBP binding and transcription activity». J. Biol. Chem. (United States) 276 (19): pp. 15886–92. doi:. ISSN 0021-9258. PMID 11278496.
- ↑ Sun, X; Ma D, Sheldon M, Yeung K, Reinberg D (Oct. 1994). «Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription». Genes Dev. (UNITED STATES) 8 (19): pp. 2336–48. ISSN 0890-9369. PMID 7958900.
- ↑ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). «Large-scale mapping of human protein-protein interactions by mass spectrometry». Mol. Syst. Biol. (England) 3: pp. 89. doi:. PMID 17353931.
- ↑ Teichmann, M; Wang Z, Martinez E, Tjernberg A, Zhang D, Vollmer F, Chait B T, Roeder R G (Nov. 1999). «Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 96 (24): pp. 13720–5. ISSN 0027-8424. PMID 10570139.
Enlaces externos
Categorías:- Genes del cromosoma 14
- Factores de transcripción
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