GTF2F1

GTF2F1
Subunidad 1 del factor iniciador de la transcripción IIF
Protein GTF2F1 PDB 1f3u.png
Estructura tridimensional de la proteína GTF2F1.
HUGO 4652
Símbolo GTF2F1
Símbolos alt. BTF4; RAP74; TF2F1; TFIIF
Datos genéticos
Locus Cr. 19 p13.3
Bases de datos
Entrez 2962
OMIM 189968
PDB 1f3u
RefSeq NP_002087
UniProt P35269

La subunidad 1 del factor iniciador de la transcripción IIA (GTF2A1) es una proteína codificada en humanos por el gen gtf2A1.[1] [2]

Contenido

Interacciones

La proteína GTF2F1 ha demostrado ser capaz de interaccionar con:

Véase también

  • Factor de transcripción II F

Referencias

  1. ↑ DeJong J, Roeder RG (Dec 1993). «A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA». Genes Dev 7 (11):  pp. 2220–34. PMID 8224848. 
  2. ↑ «Entrez Gene: GTF2A1 general transcription factor IIA, 1, 19/37kDa».
  3. ↑ Dikstein, R; Ruppert S, Tjian R (Mar. 1996). «TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74». Cell (UNITED STATES) 84 (5):  pp. 781–90. ISSN 0092-8674. PMID 8625415. 
  4. ↑ a b Ruppert, S; Tjian R (Nov. 1995). «Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation». Genes Dev. (UNITED STATES) 9 (22):  pp. 2747–55. ISSN 0890-9369. PMID 7590250. 
  5. ↑ Siegert, J L; Robbins P D (Jan. 1999). «Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250». Mol. Cell. Biol. (UNITED STATES) 19 (1):  pp. 846–54. ISSN 0270-7306. PMID 9858607. 
  6. ↑ a b Malik, S; Guermah M, Roeder R G (Mar. 1998). «A dynamic model for PC4 coactivator function in RNA polymerase II transcription». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 95 (5):  pp. 2192–7. ISSN 0027-8424. PMID 9482861. 
  7. ↑ Kim, M K; Nikodem V M (Oct. 1999). «hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation». Mol. Cell. Biol. (UNITED STATES) 19 (10):  pp. 6833–44. ISSN 0270-7306. PMID 10490622. 
  8. ↑ a b c d e f Scully, R; Anderson S F, Chao D M, Wei W, Ye L, Young R A, Livingston D M, Parvin J D (May. 1997). «BRCA1 is a component of the RNA polymerase II holoenzyme». Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 94 (11):  pp. 5605–10. ISSN 0027-8424. PMID 9159119. 
  9. ↑ Archambault, J; Pan G, Dahmus G K, Cartier M, Marshall N, Zhang S, Dahmus M E, Greenblatt J (Oct. 1998). «FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO». J. Biol. Chem. (UNITED STATES) 273 (42):  pp. 27593–601. ISSN 0021-9258. PMID 9765293. 
  10. ↑ Cho, H; Orphanides G, Sun X, Yang X J, Ogryzko V, Lees E, Nakatani Y, Reinberg D (Sep. 1998). «A human RNA polymerase II complex containing factors that modify chromatin structure». Mol. Cell. Biol. (UNITED STATES) 18 (9):  pp. 5355–63. ISSN 0270-7306. PMID 9710619. 
  11. ↑ Suñé, C; Hayashi T, Liu Y, Lane W S, Young R A, Garcia-Blanco M A (Oct. 1997). «CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription». Mol. Cell. Biol. (UNITED STATES) 17 (10):  pp. 6029–39. ISSN 0270-7306. PMID 9315662. 
  12. ↑ Joliot, V; Demma M, Prywes R (Feb. 1995). «Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor». Nature (ENGLAND) 373 (6515):  pp. 632–5. doi:10.1038/373632a0. ISSN 0028-0836. PMID 7854423. 
  13. ↑ Zhu, H; Joliot V, Prywes R (Feb. 1994). «Role of transcription factor TFIIF in serum response factor-activated transcription». J. Biol. Chem. (UNITED STATES) 269 (5):  pp. 3489–97. ISSN 0021-9258. PMID 8106390. 
  14. ↑ Fang, S M; Burton Z F (May. 1996). «RNA polymerase II-associated protein (RAP) 74 binds transcription factor (TF) IIB and blocks TFIIB-RAP30 binding». J. Biol. Chem. (UNITED STATES) 271 (20):  pp. 11703–9. ISSN 0021-9258. PMID 8662660. 

Enlaces externos


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