- ITGB3BP
-
Proteína centromérica R HUGO 6157 Símbolo ITGB3BP Símbolos alt. CENP-R, CENPR, HSU37139, NRIF3, TAP20 Datos genéticos Locus Cr. 1 p31.3 Bases de datos Entrez 23421 OMIM 605494 RefSeq NP_055103 UniProt Q13352 La proteína centromérica R (ITGB3BP) es una proteína que es codificada, en humanos, por el gen itgb3BP.[1] [2] [3]
Interacciones
La proteína centromérica R ha demostrado ser capaz de interaccionar con:
- Receptor X retinoide gamma[4]
- Ciclina A2[5]
- NFKB1[6]
- Receptor X retinoide alfa[2]
- Receptor de hormona tiroidea alfa[4] [2]
- CD61[7] [1]
Referencias
- ↑ a b Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, Ginsberg MH (Dec 1995). «Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit». J Cell Biol 131 (3): pp. 807–16. PMID 7593198.
- ↑ a b c Li D, Desai-Yajnik V, Lo E, Schapira M, Abagyan R, Samuels HH (Feb 2000). «NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors». Mol Cell Biol 19 (10): pp. 7191–202. PMID 10490654.
- ↑ «Entrez Gene: ITGB3BP integrin beta 3 binding protein (beta3-endonexin)».
- ↑ a b Li, D; Wang F, Samuels H H (Dec. 2001). «Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation». Mol. Cell. Biol. (United States) 21 (24): pp. 8371–84. doi:. ISSN 0270-7306. PMID 11713274.
- ↑ Ohtoshi, A; Maeda T, Higashi H, Ashizawa S, Yamada M, Hatakeyama M (Jan. 2000). «beta3-endonexin as a novel inhibitor of cyclin A-associated kinase». Biochem. Biophys. Res. Commun. (UNITED STATES) 267 (3): pp. 947–52. doi:. ISSN 0006-291X. PMID 10673397.
- ↑ Besta, Felicitas; Massberg Steffen, Brand Korbinian, Müller Elke, Page Sharon, Grüner Sabine, Lorenz Michael, Sadoul Karin, Kolanus Waldemar, Lengyel Ernst, Gawaz Meinrad (Oct. 2002). «Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor». J. Cell. Sci. (England) 115 (Pt 20): pp. 3879–88. ISSN 0021-9533. PMID 12244126.
- ↑ Fujimoto, Tetsuro-Takahiro; Katsutani Shinya, Shimomura Takeshi, Fujimura Kingo (Jan. 2002). «Novel alternatively spliced form of beta(3)-endonexin». Thromb. Res. (United States) 105 (1): pp. 63–70. ISSN 0049-3848. PMID 11864709.
Categorías:- Genes del cromosoma 1
- Factores de transcripción
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