KLF5

KLF5
Factor 5 Kruppel-like
HUGO 6349
Símbolo KLF5
Símbolos alt. BTEB2; CKLF; IKLF
Datos genéticos
Locus Cr. 13 q22.1
Bases de datos
Entrez 688
OMIM 602903
RefSeq NP_001721
UniProt Q13887

El factor 5 Kruppel-like (KLF5) es un factor de transcripción codificado en humanos por el gen klf5.[1] [2]

Esta proteína pertenece a la subfamilia Kruppel-like de proteínas con dedos de zinc. Debido a que la proteína se localiza en el núcleo celular y se une a elementos de respuesta del factor de crecimiento epidérmico, se cree que puede ser un factor de transcripción.[2]

Contenido

Interacciones

La proteína KLF5 ha demostrado ser capaz de interaccionar con:

  • Proteína SET[3]

Véase también

Referencias

  1. Sogawa K, Imataka H, Yamasaki Y, Kusume H, Abe H, Fujii-Kuriyama Y (May 1993). «cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2». Nucleic Acids Res 21 (7):  pp. 1527–32. doi:10.1093/nar/21.7.1527. PMID 8479902. 
  2. a b «Entrez Gene: KLF5 Kruppel-like factor 5 (intestinal)».
  3. Miyamoto, Saku; Suzuki Toru, Muto Shinsuke, Aizawa Kenichi, Kimura Akatsuki, Mizuno Yoshiko, Nagino Tomoko, Imai Yasushi, Adachi Naruhiko, Horikoshi Masami, Nagai Ryozo (Dec. 2003). «Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain». Mol. Cell. Biol. (United States) 23 (23):  pp. 8528–41. doi:10.1128/MCB.23.23.8528-8541.2003. ISSN 0270-7306. PMID 14612398. 

Enlaces externos


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