MKNK2

MKNK2
Serina/treonina quinasa 2 de interacción con MAP quinasa
Protein MKNK2 PDB 2ac3.png
Estructura tridimensional de la proteína MKNK2.
HUGO 7111
Símbolo MKNK2
Símbolos alt. GPRK7, MNK2
Datos genéticos
Locus Cr. 19 p13.3
Bases de datos
Entrez 2872
OMIM 605069
PDB 2ac3
RefSeq NP_060042
UniProt Q9HBH9

La serina/treonina quinasa 2 de interacción con MAP quinasa (MKNK2) es una enzima con actividad serina/treonina quinasa codificada en humanos por el gen mknk2.[1] [2]

Interacciones

La proteína MKNK2 ha demostrado ser capaz de interaccionar con:

Referencias

  1. ↑ Slentz-Kesler K, Moore JT, Lombard M, Zhang J, Hollingsworth R, Weiner MP (Oct 2000). «Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta». Genomics 69 (1):  pp. 63–71. doi:10.1006/geno.2000.6299. PMID 11013076. 
  2. ↑ «Entrez Gene: MKNK2 MAP kinase interacting serine/threonine kinase 2».
  3. ↑ a b Scheper, Gert C; Parra Josep L, Wilson Mary, Van Kollenburg Barbara, Vertegaal Alfred C O, Han Ze-Guang, Proud Christopher G (Aug. 2003). «The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization». Mol. Cell. Biol. (United States) 23 (16):  pp. 5692–705. ISSN 0270-7306. PMID 12897141. 
  4. ↑ Waskiewicz, A J; Flynn A, Proud C G, Cooper J A (Apr. 1997). «Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2». EMBO J. (ENGLAND) 16 (8):  pp. 1909–20. doi:10.1093/emboj/16.8.1909. ISSN 0261-4189. PMID 9155017. 

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