MKNK1

MKNK1
Serina/treonina quinasa 1 de interacción con MAP quinasa
Protein MKNK1 PDB 2hw6.png
Estructura tridimensional de la proteína MKNK1.
HUGO 7110
Símbolo MKNK1
Símbolos alt. MNK1
Datos genéticos
Locus Cr. 1 p33
Bases de datos
Entrez 8569
OMIM 606724
PDB 2hw6
RefSeq NP_003675
UniProt Q9BUB5

La serina/treonina quinasa 1 de interacción con MAP quinasa (MKNK1) es una enzima con actividad serina/treonina quinasa codificada en humanos por el gen mknk1.[1] [2]

Interacciones

La proteína MKNK1 ha demostrado ser capaz de interaccionar con:

Referencias

  1. ↑ Fukunaga R, Hunter T (Jun 1997). «MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates». EMBO J 16 (8):  pp. 1921–33. doi:10.1093/emboj/16.8.1921. PMID 9155018. 
  2. ↑ «Entrez Gene: MKNK1 MAP kinase interacting serine/threonine kinase 1».
  3. ↑ Waskiewicz, A J; Flynn A, Proud C G, Cooper J A (Apr. 1997). «Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2». EMBO J. (ENGLAND) 16 (8):  pp. 1909–20. doi:10.1093/emboj/16.8.1909. ISSN 0261-4189. PMID 9155017. 
  4. ↑ Pyronnet, S; Imataka H, Gingras A C, Fukunaga R, Hunter T, Sonenberg N (Jan. 1999). «Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E». EMBO J. (ENGLAND) 18 (1):  pp. 270–9. doi:10.1093/emboj/18.1.270. ISSN 0261-4189. PMID 9878069. 

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