- TRAP1
-
Proteína 1 asociada al receptor de TNF HUGO 16264 Símbolo TRAP1 Símbolos alt. HSP75; HSP90L Datos genéticos Locus Cr. 16 p13.3 Bases de datos Entrez 10131 OMIM 606219 RefSeq NP_057376 UniProt Q12931 La proteína 1 asociada al receptor de TNF (TRAP1) es una proteína de choque térmico mitocondrial de 75 kDa codificada en humanos por el gen TRAP1.[1] [2] [3]
Interacciones
La proteína TRAP1 ha demostrado ser capaz de interaccionar con:
- EXT2[4]
- EXT1[4]
- Proteína del retinoblastoma[5]
Referencias
- ↑ Felts SJ, Owen BA, Nguyen P, Trepel J, Donner DB, Toft DO (Mar 2000). «The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties». J Biol Chem 275 (5): pp. 3305–12. PMID 10652318.
- ↑ Song HY, Dunbar JD, Zhang YX, Guo D, Donner DB (Mar 1995). «Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor». J Biol Chem 270 (8): pp. 3574–81. PMID 7876093.
- ↑ «Entrez Gene: TRAP1 TNF receptor-associated protein 1».
- ↑ a b Simmons, A D; Musy M M, Lopes C S, Hwang L Y, Yang Y P, Lovett M (Nov. 1999). «A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses». Hum. Mol. Genet. (ENGLAND) 8 (12): pp. 2155–64. ISSN 0964-6906. PMID 10545594.
- ↑ Chen, C F; Chen Y, Dai K, Chen P L, Riley D J, Lee W H (Sep. 1996). «A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock». Mol. Cell. Biol. (UNITED STATES) 16 (9): pp. 4691–9. ISSN 0270-7306. PMID 8756626.
Categorías:- Genes del cromosoma 16
- Proteínas humanas
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