CD18

CD18

CD18

CD18
Identificadores
Símbolo ITGB2
OMIM 600065
Otros datos
Locus Cr. 21 [1]

En inmunología se denomina CD18 (del inglés cluster of differentiation) a un tipo de antígeno CD propio del sistema inmune de mamíferos. Se caracteriza por poseer un peso molecular de 95 kDa y su naturaleza bioquímica lo encuadra dentro de la familia de integrinas β. Su función biológica en la célula es: asociarse, como subunidad de integrina β2 que es, a CD11a, b, c y d, esto es, media en la adhesión celular e interviene en la ruta de transducción de señal[1] . Se expresa específicamente en leucocitos.[2]

Referencias

  1. «Entrez Gene: ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)».
  2. Janeway, Jr et al (2000). Inmunobiología. Masson, SA. ISBN 84-458-1176-2.
Obtenido de "CD18"

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